综上所述，腹侧被盖区星形胶质细胞的钙信号及其神经活性物质释放对于维持情绪平衡至关重要：其功能一旦受损，在平静状态下影响或许不大，但会显著增加个体面对慢性压力时的脆弱性，削弱其抵御焦虑与抑郁的能力，这表明此类胶质细胞在情绪保护中充当着“缓冲垫”的角色。
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Lokke redesigned Mack for the fourth issue, significantly reducing size and simplifying facial features. Mack lost whiskers, retained distinctive ears and buck teeth, and acquired torso and limbs. Gesturing now became feasible.
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